Ambisome package insert pdf file

This assay is intended for the quantitative determination ambiwome inorganic phosphorus in human serum, plasma or urine samples. Ambisome amphotericin b liposome for injection astellas. However, the clinical relevance of drug resistance has not been. Specific dosage and duration of therapy depend on nature of infection being treated. The patient information leaflet pil is the leaflet included in the pack with a medicine. Abelcet lipid complex 5 mgml concentrate for dispersion for infusion. One compassionate use study enrolled patients who had failed amphotericin b deoxycholate therapy or who were unable to receive amphotericin b deoxycholate. The recommended concentration for intravenous infusion is 0. Ambisome ambisome amphotericin b liposome for injection. Each vial contains 50 mg of amphotericin b, usp, intercalated into a liposomal membrane consisting of approximately 0.

Ambisome is contraindicated in those patients who have demonstrated or have a known hypersensitivity to amphotericin b deoxycholate or any other constituents of the product, unless benefit of therapy outweighs the risk warnings and precautions. Pdf liposomal amphotericin b ambisome researchgate. Read all of this leaflet carefully before you start. However, the following drugs are known to interact with amphotericin b and may interact with ambisome. Page 5 of 32 at doses comparable to those used in adults on a per kilogram body weight basis, no dosage adjustment is. March 2012 description am b isome for injection is a sterile, nonpyrogenic lyophilized product for intravenous infusion. Product monograph prambisome liposomal amphotericin b. B liposome for injection and its side effects and prescribing information. Liposomal amphotericin b is fda approved for the treatment of cryptococcal. Dosage of amphotericin b as ambisome must be adjusted to the specific requirements of each patient. Ambisome liposomal 50 mg powder for dispersion for infusion emc.

One controlled trial compared the efficacy and safety of ambisome to amphotericin b in hiv patients with cryptococcal meningitis. Ambisome amphotericin b liposome for injection revised. Patientdays are derived from the calculation of total milligrams soldaverage grams. Learn about ambisome amphotericin b liposome for injection and its side effects and prescribing information. Ambisome for injection is a sterile, nonpyrogenic lyophilized product for intravenous infusion. Ambisome is presented in 15 ml, 20 ml or 30 ml sterile, type i glass vials.

Anaphylaxis has been reported with amphotericin bcontaining drugs, including ambisome. Ambisome package insert pdf name of the medicinal product. For treatment of systemic mycotic infections, therapy is. Liposomes are closed, spherical vesicles formed from a variety of amphiphilic substances such as phospholipids.